Revelation 16:1-2

Then I heard a loud voice from the temple, saying to the seven angels, “Go and pour out on the earth the seven bowls of the wrath and indignation of God.” [Ps 69:24; Is 66:6] So the first angel went and poured out his bowl on the earth; and loathsome and malignant sores came on the people who had the mark of the beast and who worshiped his image. [Ex 9:10, 11; Deut 28:35]